4. Maturation of the eukaryotic pre-mRNA transcript

Figure 19: Use of sequences located at the beginning and at the end of exons and introns for splicing

Figure 19: Use of sequences located at the beginning and at the end of exons and introns for splicing

4.3 Intron splicing

Conserved sequences are found at both the beginning and end of introns (GU and AG).

The 3' end of exon 1 binds to the 5' end of exon 2, and the intron is eliminated.

Intron splicing is made possible by a ribo-nucleoproteic complex named spliceosome containing proteins and snRNAs.