4. Post-translational modifications

Figure 24: Phosphate group

Figure 24: Phosphate group

4.2 Post-translational modifications

c. Modification of some amino acids

Upon translation, some amino acids are modified. Among the most frequently occurring modifications:

  • Addition of a –OH, -CH3, or -CO-CH3 group

  • Addition of a phosphate group

  • Binding of a ubiquitin protein (=ubiquitination)